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Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

The HIV-1 envelope protein (Env) of early-replicating viruses encodes several distinct transmission signatures. One such signature involves a reduced number of potential N-linked glycosylation sites (PNGs). This transmission signature underscores the importance of posttranslational modifications in...

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Detalles Bibliográficos
Autores principales: Yolitz, Jason, Schwing, Catherine, Chang, Julia, Van Ryk, Donald, Nawaz, Fatima, Wei, Danlan, Cicala, Claudia, Arthos, James, Fauci, Anthony S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877976/
https://www.ncbi.nlm.nih.gov/pubmed/29463753
http://dx.doi.org/10.1073/pnas.1722627115