Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

Corneal neovascularization is a sight-threatening condition caused by angiogenesis in the normally avascular cornea. Neovascularization of the cornea is often associated with an inflammatory response, thus targeting VEGF-A alone yields only a limited efficacy. The NF-κB signaling pathway plays impor...

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Detalles Bibliográficos
Autores principales: Lennikov, Anton, Mirabelli, Pierfrancesco, Mukwaya, Anthony, Schaupper, Mira, Thangavelu, Muthukumar, Lachota, Mieszko, Ali, Zaheer, Jensen, Lasse, Lagali, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878206/
https://www.ncbi.nlm.nih.gov/pubmed/29332242
http://dx.doi.org/10.1007/s10456-018-9594-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878206/
https://www.ncbi.nlm.nih.gov/pubmed/29332242
http://dx.doi.org/10.1007/s10456-018-9594-9

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