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Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay

The aim of the present study was to identify key antidiabetic nodes in the livers of pioglitazone-treated type 2 diabetes mellitus Sprague-Dawley rats by transcriptomic and proteomic analysis. Rats were randomly divided into the control, the diabetes model, and the pioglitazone-treated groups. After...

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Detalles Bibliográficos
Autores principales: Lu, Zhong-Xia, Xu, Wen-Jun, Wu, Yang-Sheng, Li, Chang-Yu, Chen, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878868/
https://www.ncbi.nlm.nih.gov/pubmed/29744368
http://dx.doi.org/10.1155/2018/8120847