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Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways

Liver fibrosis is characterized by activated hepatic stellate cells (HSC) and extracellular matrix accumulation. Blocking the activation of HSC and the inflammation response are two major effective therapeutic strategies for liver fibrosis. In addition to the long history of using andrographolide (A...

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Detalles Bibliográficos
Autores principales: Lin, Liteng, Li, Rui, Cai, Mingyue, Huang, Jingjun, Huang, Wensou, Guo, Yongjian, Yang, Liuhong, Yang, Guizhi, Lan, Tian, Zhu, Kangshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878918/
https://www.ncbi.nlm.nih.gov/pubmed/29743985
http://dx.doi.org/10.1155/2018/7808656