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DNA Area and NETosis Analysis (DANA): a High-Throughput Method to Quantify Neutrophil Extracellular Traps in Fluorescent Microscope Images

BACKGROUND: Neutrophil extracellular traps (NETs), extracellular structures composed of decondensed chromatin and antimicrobial molecules, are released in a process called NETosis. NETs, which are part of normal host defense, have also been implicated in multiple human diseases. Unfortunately, metho...

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Detalles Bibliográficos
Autores principales: Rebernick, Ryan, Fahmy, Lauren, Glover, Christopher, Bawadekar, Mandar, Shim, Daeun, Holmes, Caitlyn L., Rademacher, Nicole, Potluri, Hemanth, Bartels, Christie M., Shelef, Miriam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878938/
https://www.ncbi.nlm.nih.gov/pubmed/29618953
http://dx.doi.org/10.1186/s12575-018-0072-y