Validation of the Mandarin Chinese version of the Leicester Cough Questionnaire in non‐small cell lung cancer patients after surgery

BACKGROUND: There are no validated and reliable cough‐specific instruments to assess health‐related quality of life with respect to postoperative cough in non‐small cell lung cancer (NSCLC) patients. We used the Leicester Cough Questionnaire in Mandarin‐Chinese (LCQ‐MC) and investigated the validity, reliability, and repeatability of this instrument. METHODS: A total of 130 NSCLC patients (average age 58.75 ± 9.43 years, 65 men, 65 women) completed the LCQ‐MC, cough Visual Analogue Scale (VAS), Cough Symptom Score (CSS), Hospital Anxiety and Depression Scale (HADS), and Medical Outcomes Study 36‐item Short‐Form Health Survey (SF‐36). Forty patients completed the LCQ‐MC again one week later. Concurrent validity, internal consistency, and repeatability were assessed. RESULTS: Analyses of concurrent validity showed significant correlations between the LCQ‐MC and the cough VAS (r = −0.488 to −0.660) and CSS (r = −0.495 to −0.601). The corresponding domains of the LCQ‐MC and the SF‐36 exhibited moderate correlations (r = 0.421–0.432). However, there was no significant correlation between the LCQ‐MC and the HADS (P > 0.05). Internal consistency was acceptable (Cronbach's α of 0.74–0.90). Test‐retest reliability was high (intraclass correlation coefficients of 0.89–0.95). CONCLUSION: The LCQ‐MC is a reliable, valid instrument for assessing postoperative cough in NSCLC patients.