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ALK‐rearrangement in non‐small‐cell lung cancer (NSCLC)

The ALK gene encodes a transmembrane tyrosine kinase receptor. ALK is physiologically expressed in the nervous system during embryogenesis, but its expression decreases postnatally. ALK first emerged in the field of oncology in 1994 when it was identified to fuse to NPM1 in anaplastic large‐cell lym...

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Detalles Bibliográficos
Autores principales: Du, Xue, Shao, Yun, Qin, Hai‐Feng, Tai, Yan‐Hong, Gao, Hong‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879058/
https://www.ncbi.nlm.nih.gov/pubmed/29488330
http://dx.doi.org/10.1111/1759-7714.12613