Identification of Novel Melanin Synthesis Inhibitors From Crataegus pycnoloba Using an in Vivo Zebrafish Phenotypic Assay

Zebrafish has emerged as a powerful model organism for high throughput drug screening. Several morphological criteria, transgenic lines and in situ expression screens have been developed to identify novel bioactive compounds and their mechanism of action. Here, we used the inhibition of melanogenesi...

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Detalles Bibliográficos
Autores principales: Agalou, Adamantia, Thrapsianiotis, Michael, Angelis, Apostolis, Papakyriakou, Athanasios, Skaltsounis, Alexios-Leandros, Aligiannis, Nektarios, Beis, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879087/
https://www.ncbi.nlm.nih.gov/pubmed/29632489
http://dx.doi.org/10.3389/fphar.2018.00265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879087/
https://www.ncbi.nlm.nih.gov/pubmed/29632489
http://dx.doi.org/10.3389/fphar.2018.00265

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