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The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

INTRODUCTION/OBJECTIVES: In 2012, hypocomplementemia was included in the classification criteria of systemic lupus erythematosus (SLE). The suggested measurement of C3 or C4 often reflect disease activity poorly. Our objective was to establish an assay measuring C3dg, which is generated following co...

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Detalles Bibliográficos
Autores principales: Troldborg, Anne, Jensen, Lisbeth, Deleuran, Bent, Stengaard-Pedersen, Kristian, Thiel, Steffen, Jensenius, Jens Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879092/
https://www.ncbi.nlm.nih.gov/pubmed/29632534
http://dx.doi.org/10.3389/fimmu.2018.00581