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Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1

Two major aspects of systemic lupus erythematosus (SLE) pathogenesis that have yet to be targeted therapeutically are immune complex-initiated complement activation and neutrophil extracellular trap (NET) formation by neutrophils. Here, we report in vitro testing of peptide inhibitor of complement C...

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Detalles Bibliográficos
Autores principales: Hair, Pamela S., Enos, Adrianne I., Krishna, Neel K., Cunnion, Kenji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879100/
https://www.ncbi.nlm.nih.gov/pubmed/29632531
http://dx.doi.org/10.3389/fimmu.2018.00558