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Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents
There is now compelling evidence that tumor necrosis factor (TNF)–TNF receptor type II (TNFR2) interaction plays a decisive role in the activation, expansion, and phenotypical stability of suppressive CD4(+)Foxp3(+) regulatory T cells (Tregs). In an effort to translate this basic research finding in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879105/ https://www.ncbi.nlm.nih.gov/pubmed/29632537 http://dx.doi.org/10.3389/fimmu.2018.00594 |