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Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents

There is now compelling evidence that tumor necrosis factor (TNF)–TNF receptor type II (TNFR2) interaction plays a decisive role in the activation, expansion, and phenotypical stability of suppressive CD4(+)Foxp3(+) regulatory T cells (Tregs). In an effort to translate this basic research finding in...

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Detalles Bibliográficos
Autores principales: Zou, Huimin, Li, Ruixin, Hu, Hao, Hu, Yuanjia, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879105/
https://www.ncbi.nlm.nih.gov/pubmed/29632537
http://dx.doi.org/10.3389/fimmu.2018.00594