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PKCδ-Mediated Nox2 Activation Promotes Fluid-Phase Pinocytosis of Antigens by Immature Dendritic Cells

AIMS: Macropinocytosis is a major endocytic pathway by which dendritic cells (DCs) internalize antigens in the periphery. Despite the importance of DCs in the initiation and control of adaptive immune responses, the signaling mechanisms mediating DC macropinocytosis of antigens remain largely unknow...

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Detalles Bibliográficos
Autores principales: Singla, Bhupesh, Ghoshal, Pushpankur, Lin, Huiping, Wei, Qingqing, Dong, Zheng, Csányi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879126/
https://www.ncbi.nlm.nih.gov/pubmed/29632528
http://dx.doi.org/10.3389/fimmu.2018.00537