Combined in Vitro and in Silico Studies for the Anticholinesterase Activity and Pharmacokinetics of Coumarinyl Thiazoles and Oxadiazoles

In a continuation of our previous work for the exploration of novel enzyme inhibitors, two new coumarin-thiazole 6(a–o) and coumarin-oxadiazole 11(a–h) hybrids have been designed and synthesized. All the compounds were characterized by (1)H- and (13)C-NMR spectroscopy and elemental analysis. New hyb...

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Detalles Bibliográficos
Autores principales: Ibrar, Aliya, Khan, Ajmal, Ali, Majid, Sarwar, Rizwana, Mehsud, Saifullah, Farooq, Umar, Halimi, Syed M. A., Khan, Imtiaz, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879128/
https://www.ncbi.nlm.nih.gov/pubmed/29632858
http://dx.doi.org/10.3389/fchem.2018.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879128/
https://www.ncbi.nlm.nih.gov/pubmed/29632858
http://dx.doi.org/10.3389/fchem.2018.00061

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