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Combined in Vitro and in Silico Studies for the Anticholinesterase Activity and Pharmacokinetics of Coumarinyl Thiazoles and Oxadiazoles
In a continuation of our previous work for the exploration of novel enzyme inhibitors, two new coumarin-thiazole 6(a–o) and coumarin-oxadiazole 11(a–h) hybrids have been designed and synthesized. All the compounds were characterized by (1)H- and (13)C-NMR spectroscopy and elemental analysis. New hyb...
Autores principales: | Ibrar, Aliya, Khan, Ajmal, Ali, Majid, Sarwar, Rizwana, Mehsud, Saifullah, Farooq, Umar, Halimi, Syed M. A., Khan, Imtiaz, Al-Harrasi, Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879128/ https://www.ncbi.nlm.nih.gov/pubmed/29632858 http://dx.doi.org/10.3389/fchem.2018.00061 |
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