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Ezh2 Regulates Activation-Induced CD8(+) T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression

Transition from resting to cell cycle in response to antigenic stimulation is an essential step for naïve CD8(+) T cells to differentiate to effector and memory cells. Leaving the resting state requires dramatic changes of chromatin status in the key cell cycle inhibitors but the details of these co...

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Detalles Bibliográficos
Autores principales: Chen, Guobing, Subedi, Kalpana, Chakraborty, Sayantan, Sharov, Alexie, Lu, Jian, Kim, Jaekwan, Mi, Xiaofan, Wersto, Robert, Sung, Myong-Hee, Weng, Nan-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879148/
https://www.ncbi.nlm.nih.gov/pubmed/29632530
http://dx.doi.org/10.3389/fimmu.2018.00549