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Ezh2 Regulates Activation-Induced CD8(+) T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression
Transition from resting to cell cycle in response to antigenic stimulation is an essential step for naïve CD8(+) T cells to differentiate to effector and memory cells. Leaving the resting state requires dramatic changes of chromatin status in the key cell cycle inhibitors but the details of these co...
Autores principales: | Chen, Guobing, Subedi, Kalpana, Chakraborty, Sayantan, Sharov, Alexie, Lu, Jian, Kim, Jaekwan, Mi, Xiaofan, Wersto, Robert, Sung, Myong-Hee, Weng, Nan-ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879148/ https://www.ncbi.nlm.nih.gov/pubmed/29632530 http://dx.doi.org/10.3389/fimmu.2018.00549 |
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