Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma

BACKGROUND: The phenomenon that malignant cells can acquire stemness under specific stimuli, encompassed under the concept of cancer cell plasticity, has been well-described in epithelial malignancies. To our knowledge, cancer cell plasticity has not yet been described in hematopoietic cancers. To i...

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Detalles Bibliográficos
Autores principales: Wu, Chengsheng, Gupta, Nidhi, Huang, Yung-Hsing, Zhang, Hai-Feng, Alshareef, Abdulraheem, Chow, Alexandra, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879562/
https://www.ncbi.nlm.nih.gov/pubmed/29609590
http://dx.doi.org/10.1186/s12885-018-4300-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879562/
https://www.ncbi.nlm.nih.gov/pubmed/29609590
http://dx.doi.org/10.1186/s12885-018-4300-2

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