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Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma
BACKGROUND: The phenomenon that malignant cells can acquire stemness under specific stimuli, encompassed under the concept of cancer cell plasticity, has been well-described in epithelial malignancies. To our knowledge, cancer cell plasticity has not yet been described in hematopoietic cancers. To i...
Autores principales: | Wu, Chengsheng, Gupta, Nidhi, Huang, Yung-Hsing, Zhang, Hai-Feng, Alshareef, Abdulraheem, Chow, Alexandra, Lai, Raymond |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879562/ https://www.ncbi.nlm.nih.gov/pubmed/29609590 http://dx.doi.org/10.1186/s12885-018-4300-2 |
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