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Palmitate-induced Slc2a4/GLUT4 downregulation in L6 muscle cells: evidence of inflammatory and endoplasmic reticulum stress involvement
BACKGROUND: Obesity is strongly associated to insulin resistance, inflammation, and elevated plasma free fatty acids, but the mechanisms behind this association are not fully comprehended. Evidences suggest that endoplasmic reticulum (ER) stress may play a role in this complex pathophysiology. The a...
Autores principales: | Ebersbach-Silva, Patrícia, Poletto, Ana Cláudia, David-Silva, Aline, Seraphim, Patrícia Monteiro, Anhê, Gabriel Forato, Passarelli, Marisa, Furuya, Daniela Tomie, Machado, Ubiratan Fabres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879605/ https://www.ncbi.nlm.nih.gov/pubmed/29609616 http://dx.doi.org/10.1186/s12944-018-0714-8 |
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