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The dopamine D(1) receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

BACKGROUND: Dopamine receptors comprise two subgroups, G(s) protein-coupled “D(1)-like” receptors (D(1), D(5)) and G(i)-coupled “D(2)-like” receptors (D(2), D(3), D(4)). In airways, both dopamine D(1) and D(2) receptors are expressed on airway smooth muscle and regulate airway smooth muscle force. H...

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Detalles Bibliográficos
Autores principales: Matsuyama, Nao, Shibata, Sumire, Matoba, Atsuko, Kudo, Tada-aki, Danielsson, Jennifer, Kohjitani, Atsushi, Masaki, Eiji, Emala, Charles W., Mizuta, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879645/
https://www.ncbi.nlm.nih.gov/pubmed/29606146
http://dx.doi.org/10.1186/s12931-018-0757-4