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The dopamine D(1) receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium
BACKGROUND: Dopamine receptors comprise two subgroups, G(s) protein-coupled “D(1)-like” receptors (D(1), D(5)) and G(i)-coupled “D(2)-like” receptors (D(2), D(3), D(4)). In airways, both dopamine D(1) and D(2) receptors are expressed on airway smooth muscle and regulate airway smooth muscle force. H...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879645/ https://www.ncbi.nlm.nih.gov/pubmed/29606146 http://dx.doi.org/10.1186/s12931-018-0757-4 |