Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial

OBJECTIVES: To test whether administration of the antifibrinolytic drug tranexamic acid (TXA) in patients with spontaneous intracerebral haemorrhage (SICH) leads to increased prevalence of diffusion-weighted MRI-defined hyperintense ischaemic lesions (primary hypothesis) or reduced perihaematomal oe...

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Detalles Bibliográficos
Autores principales: Dineen, Rob A, Pszczolkowski, Stefan, Flaherty, Katie, Law, Zhe K, Morgan, Paul S, Roberts, Ian, Werring, David J, Al-Shahi Salman, Rustam, England, Tim, Bath, Philip M, Sprigg, Nikola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Radiology and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879748/
https://www.ncbi.nlm.nih.gov/pubmed/29431141
http://dx.doi.org/10.1136/bmjopen-2017-019930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879748/
https://www.ncbi.nlm.nih.gov/pubmed/29431141
http://dx.doi.org/10.1136/bmjopen-2017-019930

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