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Dengue virus-like particles mimic the antigenic properties of the infectious dengue virus envelope

BACKGROUND: The 4 dengue serotypes (DENV) are mosquito-borne pathogens that are associated with severe hemorrhagic disease. DENV particles have a lipid bilayer envelope that anchors two membrane glycoproteins prM and E. Two E-protein monomers form head-to-tail homodimers and three E-dimers align to...

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Detalles Bibliográficos
Autores principales: Metz, Stefan W., Thomas, Ashlie, White, Laura, Stoops, Mark, Corten, Markus, Hannemann, Holger, de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879749/
https://www.ncbi.nlm.nih.gov/pubmed/29609659
http://dx.doi.org/10.1186/s12985-018-0970-2