Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

PURPOSE: To determine if one injection of a sustained release formulation of dorzolamide in biodegradable microparticles (DPP) reduces retinal ganglion cell (RGC) loss in a rat model of glaucoma. METHODS: We injected either DPP or control microparticles intravitreally in rats. Two days later, unilat...

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Detalles Bibliográficos
Autores principales: Pitha, Ian, Kimball, Elizabeth C., Oglesby, Ericka N., Pease, Mary Ellen, Fu, Jie, Schaub, Julie, Kim, Yoo-Chun, Hu, Qi, Hanes, Justin, Quigley, Harry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879766/
https://www.ncbi.nlm.nih.gov/pubmed/29616152
http://dx.doi.org/10.1167/tvst.7.2.13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879766/
https://www.ncbi.nlm.nih.gov/pubmed/29616152
http://dx.doi.org/10.1167/tvst.7.2.13

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