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Mathematical modelling of interacting mechanisms for hypoxia mediated cell cycle commitment for mesenchymal stromal cells

BACKGROUND: Existing experimental data have shown hypoxia to be an important factor affecting the proliferation of mesenchymal stromal cells (MSCs), but the contrasting observations made at various hypoxic levels raise the questions of whether hypoxia accelerates proliferation, and how. On the other...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Ye, Hua, Yang, Aidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879778/
https://www.ncbi.nlm.nih.gov/pubmed/29606139
http://dx.doi.org/10.1186/s12918-018-0560-3