Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury

Ischemic brain injury triggers neuronal cell death by apoptosis via caspase activation and by necroptosis through activation of the receptor-interacting protein kinases (RIPK) associated with the tumor necrosis factor-alpha (TNF-α)/death receptor. Recent evidence shows RIPK inhibitors are neuroprote...

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Detalles Bibliográficos
Autores principales: Cruz, Shelly A., Qin, Zhaohong, Stewart, Alexandre F.R., Chen, Hsiao-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879896/
https://www.ncbi.nlm.nih.gov/pubmed/29557374
http://dx.doi.org/10.4103/1673-5374.226394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879896/
https://www.ncbi.nlm.nih.gov/pubmed/29557374
http://dx.doi.org/10.4103/1673-5374.226394

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