Cargando…

Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection

BACKGROUND: The native pre-fusion structure of gp120/gp41 complex of human immunodeficiency virus type 1 was recently revealed. In the model, the helices of gp41 (α6, α7, α8, and α9) form a four-helix collar underneath trimeric gp120. Gp41 is a class I fusion protein and mediates membrane fusion by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Dehua, Wang, Hongyun, Yamamoto, Mizuki, Song, Jiping, Zhang, Rui, Du, Qingling, Kawaguchi, Yasushi, Inoue, Jun-ichiro, Matsuda, Zene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879932/ https://www.ncbi.nlm.nih.gov/pubmed/29609648 http://dx.doi.org/10.1186/s12977-018-0410-9

Ejemplares similares

Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion
por: Melikyan, Grigory B., et al.
Publicado: (2000)

Resistance to N-peptide fusion inhibitors correlates with thermodynamic stability of the gp41 six-helix bundle but not HIV entry kinetics
por: De Feo, Christopher J, et al.
Publicado: (2014)

Membrane topology analysis of HIV-1 envelope glycoprotein gp41
por: Liu, Shujun, et al.
Publicado: (2010)

Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41
por: Nishikawa, Hiroki, et al.
Publicado: (2008)

Anti-HIV-1 activity of cellulose acetate phthalate: Synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles
por: Neurath, A Robert, et al.
Publicado: (2002)

Engineering T-Cell Resistance to HIV-1 Infection via Knock-In of Peptides from the Heptad Repeat 2 Domain of gp41
por: Maslennikova, Alexandra, et al.
Publicado: (2022)

The Conserved Residue Arg46 in the N-Terminal Heptad Repeat Domain of HIV-1 gp41 Is Critical for Viral Fusion and Entry
por: Wang, Xiaoyi, et al.
Publicado: (2012)

Binding of HIV-1 gp41-Directed Neutralizing and Non-Neutralizing Fragment Antibody Binding Domain (Fab) and Single Chain Variable Fragment (ScFv) Antibodies to the Ectodomain of gp41 in the Pre-Hairpin and Six-Helix Bundle Conformations
por: Louis, John M., et al.
Publicado: (2014)

The Antimalarial Compound Atovaquone Inhibits Zika and Dengue Virus Infection by Blocking E Protein-Mediated Membrane Fusion
por: Yamamoto, Mizuki, et al.
Publicado: (2020)

The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein
por: Miyauchi, Kosuke, et al.
Publicado: (2010)

Site-specific Isopeptide Bridge Tethering of Chimeric gp41 N-terminal Heptad Repeat Helical Trimers for the Treatment of HIV-1 Infection
por: Wang, Chao, et al.
Publicado: (2016)

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus
por: Leslie, George J., et al.
Publicado: (2016)

The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat
por: Montefiori, David C., et al.
Publicado: (2021)

A Derivative of the D5 Monoclonal Antibody That Targets the gp41 N-Heptad Repeat of HIV-1 with Broad Tier-2-Neutralizing Activity
por: Rubio, Adonis A., et al.
Publicado: (2021)

The SARS-CoV heptad repeat 2 exhibits pH-induced helix formation
por: Celigoy, Jessica, et al.
Publicado: (2011)

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41
por: Sabin, Charles, et al.
Publicado: (2010)

Conserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors
por: Geng, Xiuzhu, et al.
Publicado: (2019)

NMR Structure of the FIV gp36 C-terminal Heptad Repeat and Membrane-Proximal External Region
por: Grimaldi, Manuela, et al.
Publicado: (2020)

C-terminal tail of human immunodeficiency virus gp41: functionally rich and structurally enigmatic
por: Steckbeck, Jonathan D., et al.
Publicado: (2013)

An abiotic, tetrameric, eight-helix bundle
por: Menke, Friedericke S., et al.
Publicado: (2023)

Heptad-repeat sequences in the glycoprotein of rhabdoviruses
por: Morales Coll, Julio
Publicado: (1995)

CryoET structures of immature HIV Gag reveal six-helix bundle
por: Mendonça, Luiza, et al.
Publicado: (2021)

gp41: HIV's shy protein
por: Zwick, Michael B, et al.
Publicado: (2004)

Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers
por: Kandeel, Mahmoud, et al.
Publicado: (2020)

IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis
por: Duchemin, Maxence, et al.
Publicado: (2018)

An Artificial Peptide-Based Bifunctional HIV-1 Entry Inhibitor That Interferes with Viral Glycoprotein-41 Six-Helix Bundle Formation and Antagonizes CCR5 on the Host Cell Membrane
por: Wang, Chao, et al.
Publicado: (2023)

Systematic Analysis of Intracellular Trafficking Motifs Located within the Cytoplasmic Domain of Simian Immunodeficiency Virus Glycoprotein gp41
por: Postler, Thomas S., et al.
Publicado: (2014)

Maternal Envelope gp41 Ectodomain-Specific Antibodies Are Associated With Increased Mother-to-Child Transmission of Human Immunodeficiency Virus-1
por: Naiman, Nicole E, et al.
Publicado: (2020)

Neutralizing Antibodies Targeting HIV-1 gp41
por: Caillat, Christophe, et al.
Publicado: (2020)

Engineering a two-helix bundle protein for folding studies
por: Dodson, Charlotte A., et al.
Publicado: (2010)

A four-helix bundle stores copper for methane oxidation
por: Vita, Nicolas, et al.
Publicado: (2015)

Development of Protein- and Peptide-Based HIV Entry Inhibitors Targeting gp120 or gp41
por: Pu, Jing, et al.
Publicado: (2019)

Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface
por: Torrents de la Peña, Alba, et al.
Publicado: (2021)

Neutralizing Antibodies Against a Specific Human Immunodeficiency Virus gp41 Epitope are Associated With Long-term Non-progressor Status
por: Lucar, Olivier, et al.
Publicado: (2017)

Identification of Anti-gp41 Monoclonal Antibodies That Effectively Target Cytotoxic Immunoconjugates to Cells Infected with Human Immunodeficiency Virus, Type 1
por: Klug, Grant, et al.
Publicado: (2023)

Helix-A peptide prevents gp120-mediated neuronal loss
por: Avdoshina, Valeria, et al.
Publicado: (2019)

An Accurate Confirmation of Human Immunodeficiency Virus Type 1 (HIV-1) and 2 (HIV-2) Infections with a Dot blot assay Using Recombinant p24, gp41, gp120 and gp36 Antigens
por: Ravanshad, Mehrdad, et al.
Publicado: (2004)

Antiviral properties of two trimeric recombinant gp41 proteins
por: Delcroix-Genête, Delphine, et al.
Publicado: (2006)

Unfolding and Folding of the Three-Helix Bundle Protein KIX in the Absence of Solvent
por: Schennach, Moritz, et al.
Publicado: (2016)

The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling
por: Ishida, Hiroaki, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a5i30101iqptfkn81rcuueod7c