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Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p

Preliminary studies have shown that endothelial-monocyte-activating polypeptide-II (EMAP-II) and temozolomide (TMZ) alone can exert cytotoxic effects on glioma cells. This study explored whether EMAP-II can enhance the cytotoxic effects of TMZ on glioma stem cells (GSCs) and the possible mechanisms...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Liu, Libo, Xue, Yixue, Ma, Yawen, Liu, Xiaobai, Li, Zhen, Li, Zhiqing, Liu, Yunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879952/
https://www.ncbi.nlm.nih.gov/pubmed/29632473
http://dx.doi.org/10.3389/fnmol.2018.00092