Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle

BACKGROUND: Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life. Doxorubicin (DOX) is an effective cytostatic agent, which unfortunately has toxic effects on many healthy tissues. Blocking of activin rec...

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Detalles Bibliográficos
Autores principales: Hulmi, Juha J., Nissinen, Tuuli A., Räsänen, Markus, Degerman, Joni, Lautaoja, Juulia H., Hemanthakumar, Karthik Amudhala, Backman, Janne T., Ritvos, Olli, Silvennoinen, Mika, Kivelä, Riikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879968/
https://www.ncbi.nlm.nih.gov/pubmed/29230965
http://dx.doi.org/10.1002/jcsm.12265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879968/
https://www.ncbi.nlm.nih.gov/pubmed/29230965
http://dx.doi.org/10.1002/jcsm.12265

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