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miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting

BACKGROUND: A loss of muscle mass occurs as a consequence of a range of chronic and acute diseases as well as in older age. This wasting results from an imbalance of protein synthesis and degradation with a reduction in synthesis and resistance to anabolic stimulation often reported features. Riboso...

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Detalles Bibliográficos
Autores principales: Connolly, Martin, Paul, Richard, Farre‐Garros, Roser, Natanek, Samantha A., Bloch, Susannah, Lee, Jen, Lorenzo, Jose P., Patel, Harnish, Cooper, Cyrus, Sayer, Avan A., Wort, Stephen J., Griffiths, Mark, Polkey, Michael I., Kemp, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879973/
https://www.ncbi.nlm.nih.gov/pubmed/29215200
http://dx.doi.org/10.1002/jcsm.12266