Imatinib Affects the Expression of SLC22A1 in a Non-Linear Concentration-Dependent Manner Within 24 Hours

BACKGROUND: Imatinib is actively transported into cells by the organic cation transporter (OCT1), encoded by SLC22A1. As a result, the expression of SLC22A1 is considered a prognostic marker for treatment with imatinib in patients with chronic myeloid leukemia (CML). Although limited, there is confl...

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Detalles Bibliográficos
Autores principales: Tantuan, Sandhya Sreenivasan, Viljoen, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Pharmaceutical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880015/
https://www.ncbi.nlm.nih.gov/pubmed/29567937
http://dx.doi.org/10.12659/MSMBR.909124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880015/
https://www.ncbi.nlm.nih.gov/pubmed/29567937
http://dx.doi.org/10.12659/MSMBR.909124

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