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DNA Methylation variability among individuals is related to CpGs cluster density and evolutionary signatures

BACKGROUND: In recent years, epigenetics has gained a central role in the understanding of the process of natural selection. It is now clear how environmental impacts on the methylome could promote methylation variability with direct effects on disease etiology as well as phenotypic and genotypic va...

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Detalles Bibliográficos
Autores principales: Palumbo, Domenico, Affinito, Ornella, Monticelli, Antonella, Cocozza, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880022/
https://www.ncbi.nlm.nih.gov/pubmed/29606093
http://dx.doi.org/10.1186/s12864-018-4618-9