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The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells

BACKGROUND: Cancer cachexia is a cancer-induced metabolic disorder and a major cause of cancer-induced death. The constituents of cancer cachexia include an increase in energy expenditure, hepatic gluconeogenesis, fat lipolysis, and skeletal-muscle proteolysis and a decrease in body weight. The aeti...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Liu, Hongyi, Hu, Lijuan, Liu, Yunfei, Duan, Yijie, Cui, Rui, Tian, Wencong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880080/
https://www.ncbi.nlm.nih.gov/pubmed/29609556
http://dx.doi.org/10.1186/s12885-018-4271-3