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Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC)

The interpatient variability of tumor proteomes has been investigated on a large scale but many tumors display also intratumoral heterogeneity regarding morphological and genetic features. It remains largely unknown to what extent the local proteome of tumors intrinsically differs. Here, we used hep...

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Detalles Bibliográficos
Autores principales: Buczak, Katarzyna, Ori, Alessandro, Kirkpatrick, Joanna M., Holzer, Kerstin, Dauch, Daniel, Roessler, Stephanie, Endris, Volker, Lasitschka, Felix, Parca, Luca, Schmidt, Alexander, Zender, Lars, Schirmacher, Peter, Krijgsveld, Jeroen, Singer, Stephan, Beck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880102/
https://www.ncbi.nlm.nih.gov/pubmed/29363612
http://dx.doi.org/10.1074/mcp.RA117.000189