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Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC)
The interpatient variability of tumor proteomes has been investigated on a large scale but many tumors display also intratumoral heterogeneity regarding morphological and genetic features. It remains largely unknown to what extent the local proteome of tumors intrinsically differs. Here, we used hep...
Autores principales: | Buczak, Katarzyna, Ori, Alessandro, Kirkpatrick, Joanna M., Holzer, Kerstin, Dauch, Daniel, Roessler, Stephanie, Endris, Volker, Lasitschka, Felix, Parca, Luca, Schmidt, Alexander, Zender, Lars, Schirmacher, Peter, Krijgsveld, Jeroen, Singer, Stephan, Beck, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880102/ https://www.ncbi.nlm.nih.gov/pubmed/29363612 http://dx.doi.org/10.1074/mcp.RA117.000189 |
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