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CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment
Phenytoin (PHT) is an antiepileptic drug widely used in the treatment of focal epilepsy and status epilepticus, and effective in controlling focal seizures with and without tonic–clonic generalization and status epilepticus. The metabolization of PHT is carried out by two oxidative cytochrome P450 e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880189/ https://www.ncbi.nlm.nih.gov/pubmed/29636628 http://dx.doi.org/10.2147/PGPM.S108113 |