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CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment

Phenytoin (PHT) is an antiepileptic drug widely used in the treatment of focal epilepsy and status epilepticus, and effective in controlling focal seizures with and without tonic–clonic generalization and status epilepticus. The metabolization of PHT is carried out by two oxidative cytochrome P450 e...

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Detalles Bibliográficos
Autores principales:	Silvado, Carlos Eduardo, Terra, Vera Cristina, Twardowschy, Carlos Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880189/ https://www.ncbi.nlm.nih.gov/pubmed/29636628 http://dx.doi.org/10.2147/PGPM.S108113

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