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Obesity and outcome of post-menopausal women receiving adjuvant letrozole for breast cancer

INTRODUCTION: Aromatase enzyme activity is predominant in adipose tissue. This has led to speculation that aromatase activity is elevated in obese women and subsequently decreased the clinical activity of adjuvant aromatase inhibitors (AIs) in women with estrogen receptor positive (ER+) breast cance...

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Detalles Bibliográficos
Autores principales: Zekri, Jamal, Farag, Kamel, Allithy, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880223/
https://www.ncbi.nlm.nih.gov/pubmed/29662534
http://dx.doi.org/10.3332/ecancer.2018.821