Conserved microRNA targeting reveals preexisting gene dosage sensitivities that shaped amniote sex chromosome evolution

Mammalian X and Y Chromosomes evolved from an ordinary autosomal pair. Genetic decay of the Y led to X Chromosome inactivation (XCI) in females, but some Y-linked genes were retained during the course of sex chromosome evolution, and many X-linked genes did not become subject to XCI. We reconstructe...

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Detalles Bibliográficos
Autores principales: Naqvi, Sahin, Bellott, Daniel W., Lin, Kathy S., Page, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880238/
https://www.ncbi.nlm.nih.gov/pubmed/29449410
http://dx.doi.org/10.1101/gr.230433.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880238/
https://www.ncbi.nlm.nih.gov/pubmed/29449410
http://dx.doi.org/10.1101/gr.230433.117

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