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Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factors

During development, transcription factors select distinct gene programs, providing the necessary regulatory complexity for temporal and tissue-specific gene expression. How related factors retain specificity, especially when they recognize the same DNA motifs, is not understood. We address this para...

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Detalles Bibliográficos
Autores principales: Casey, Bradford H., Kollipara, Rahul K., Pozo, Karine, Johnson, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880239/
https://www.ncbi.nlm.nih.gov/pubmed/29500235
http://dx.doi.org/10.1101/gr.224360.117