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Promoter architecture determines cotranslational regulation of mRNA

Information that regulates gene expression is encoded throughout each gene but if different regulatory regions can be understood in isolation, or if they interact, is unknown. Here we measure mRNA levels for 10,000 open reading frames (ORFs) transcribed from either an inducible or constitutive promo...

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Detalles Bibliográficos
Autores principales: Espinar, Lorena, Schikora Tamarit, Miquel Àngel, Domingo, Júlia, Carey, Lucas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880241/
https://www.ncbi.nlm.nih.gov/pubmed/29567675
http://dx.doi.org/10.1101/gr.230458.117