Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11 topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic chromosomes, with hotspots controlled by chromatin and DNA sequence. To map meiotic DSBs throughout a plant genome, we purif...

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Detalles Bibliográficos
Autores principales: Choi, Kyuha, Zhao, Xiaohui, Tock, Andrew J., Lambing, Christophe, Underwood, Charles J., Hardcastle, Thomas J., Serra, Heïdi, Kim, Juhyun, Cho, Hyun Seob, Kim, Jaeil, Ziolkowski, Piotr A., Yelina, Nataliya E., Hwang, Ildoo, Martienssen, Robert A., Henderson, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880243/
https://www.ncbi.nlm.nih.gov/pubmed/29530928
http://dx.doi.org/10.1101/gr.225599.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880243/
https://www.ncbi.nlm.nih.gov/pubmed/29530928
http://dx.doi.org/10.1101/gr.225599.117

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