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Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11 topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic chromosomes, with hotspots controlled by chromatin and DNA sequence. To map meiotic DSBs throughout a plant genome, we purif...
Autores principales: | Choi, Kyuha, Zhao, Xiaohui, Tock, Andrew J., Lambing, Christophe, Underwood, Charles J., Hardcastle, Thomas J., Serra, Heïdi, Kim, Juhyun, Cho, Hyun Seob, Kim, Jaeil, Ziolkowski, Piotr A., Yelina, Nataliya E., Hwang, Ildoo, Martienssen, Robert A., Henderson, Ian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880243/ https://www.ncbi.nlm.nih.gov/pubmed/29530928 http://dx.doi.org/10.1101/gr.225599.117 |
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