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Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo

The identification of transcription factor (TF) binding sites in the genome is critical to understanding gene regulatory networks (GRNs). While ChIP-seq is commonly used to identify TF targets, it requires specific ChIP-grade antibodies and high cell numbers, often limiting its applicability. DNA ad...

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Detalles Bibliográficos
Autores principales: Tosti, Luca, Ashmore, James, Tan, Boon Siang Nicholas, Carbone, Benedetta, Mistri, Tapan K., Wilson, Valerie, Tomlinson, Simon R., Kaji, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880248/
https://www.ncbi.nlm.nih.gov/pubmed/29572359
http://dx.doi.org/10.1101/gr.227124.117