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Small-cell transformation of ALK-rearranged non-small-cell adenocarcinoma of the lung

Anaplastic lymphoma kinase (ALK) gene rearrangements are present in ∼5% of non-small-cell lung cancers (NSCLCs). These rearrangements occur because of a chromosomal inversion within the short arm of Chromosome 2, which results in the formation of the echinoderm microtubule-associated protein-like 4...

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Detalles Bibliográficos
Autores principales: Balla, Agnes, Khan, Farrah, Hampel, Kenneth J., Aisner, Dara L., Sidiropoulos, Nikoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880261/
https://www.ncbi.nlm.nih.gov/pubmed/29317428
http://dx.doi.org/10.1101/mcs.a002394