Resistance-promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient

As in other brain tumors, multiple recurrences after complete resection and irradiation of supratentorial ependymoma are common and frequently result in patient death. This standard-of-care treatment was established in the pregenomic era without the ability to evaluate the effect that mutagenic ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Christopher A., Dahiya, Sonika, Li, Tiandao, Fulton, Robert S., Smyth, Matthew D., Dunn, Gavin P., Rubin, Joshua B., Mardis, Elaine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880262/
https://www.ncbi.nlm.nih.gov/pubmed/29440180
http://dx.doi.org/10.1101/mcs.a002444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880262/
https://www.ncbi.nlm.nih.gov/pubmed/29440180
http://dx.doi.org/10.1101/mcs.a002444

Ejemplares similares