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Resistance-promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient
As in other brain tumors, multiple recurrences after complete resection and irradiation of supratentorial ependymoma are common and frequently result in patient death. This standard-of-care treatment was established in the pregenomic era without the ability to evaluate the effect that mutagenic ther...
Autores principales: | Miller, Christopher A., Dahiya, Sonika, Li, Tiandao, Fulton, Robert S., Smyth, Matthew D., Dunn, Gavin P., Rubin, Joshua B., Mardis, Elaine R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880262/ https://www.ncbi.nlm.nih.gov/pubmed/29440180 http://dx.doi.org/10.1101/mcs.a002444 |
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