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Tethering of CHROMATOR and dCTCF proteins results in decompaction of condensed bands in the Drosophila melanogaster polytene chromosomes but does not affect their transcription and replication timing

Instulator proteins are central to domain organization and gene regulation in the genome. We used ectopic tethering of CHROMATOR (CHRIZ/CHRO) and dCTCF to pre-defined regions of the genome to dissect the influence of these proteins on local chromatin organization, to analyze their interaction with o...

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Detalles Bibliográficos
Autores principales: Pokholkova, Galina V., Demakov, Sergei A., Andreenkov, Oleg V., Andreenkova, Natalia G., Volkova, Elena I., Belyaeva, Elena S., Zhimulev, Igor F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880345/
https://www.ncbi.nlm.nih.gov/pubmed/29608600
http://dx.doi.org/10.1371/journal.pone.0192634