Cargando…

Novel monoclonal antibodies targeting the microtubule-binding domain of human tau

Tauopathies including Alzheimer’s disease and Progressive Supranuclear Palsy are a diverse group of progressive neurodegenerative disorders pathologically defined by inclusions containing aberrantly aggregated, post-translationally modified tau. The tau pathology burden correlates with neurodegenera...

Descripción completa

Detalles Bibliográficos
Autores principales: Croft, Cara L., Moore, Brenda D., Ran, Yong, Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880389/
https://www.ncbi.nlm.nih.gov/pubmed/29608591
http://dx.doi.org/10.1371/journal.pone.0195211