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Specifically bound lambda repressor dimers promote adjacent non-specific binding

Genetic switches frequently include DNA loops secured by proteins. Recent studies of the lambda bacteriophage repressor (CI), showed that this arrangement in which the protein links two sets of three operators separated by approximately 2.3 kbp, optimizes both the stability and dynamics of DNA loops...

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Detalles Bibliográficos
Autores principales: Sarkar-Banerjee, Suparna, Goyal, Sachin, Gao, Ning, Mack, John, Thompson, Benito, Dunlap, David, Chattopadhyay, Krishnananda, Finzi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880393/
https://www.ncbi.nlm.nih.gov/pubmed/29608611
http://dx.doi.org/10.1371/journal.pone.0194930