Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset

Anaphase onset is an irreversible cell cycle transition that is triggered by the activation of the protease Separase. Separase cleaves the Mcd1 (also known as Scc1) subunit of Cohesin, a complex of proteins that physically links sister chromatids, triggering sister chromatid separation. Separase is...

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Detalles Bibliográficos
Autores principales: Lianga, Noel, Doré, Carole, Kennedy, Erin K., Yeh, Elaine, Williams, Elizabeth C., Fortinez, Camille Marie, Wang, Alick, Bloom, Kerry S., Rudner, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880407/
https://www.ncbi.nlm.nih.gov/pubmed/29561844
http://dx.doi.org/10.1371/journal.pgen.1007029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880407/
https://www.ncbi.nlm.nih.gov/pubmed/29561844
http://dx.doi.org/10.1371/journal.pgen.1007029

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